NFL Pick'em Week 5 2026: Games, Lines and Picks

Every NFL Week 5 game of the 2026 season with kickoff times (Eastern), spreads, moneylines, totals and final scores, to make your pick'em picks.

Games
15, Thu Oct 8 to Mon Oct 12
Byes
Panthers, Chiefs
Biggest win
Patriots by 28
Highest scoring
BUF 37 at LAR 34 (71 points)
Underdog wins
5 (Buccaneers, Packers, 49ers, Ravens, Bills)
Tiebreaker total
71 points (BUF at LAR)
15 games | lines updated Oct 12, 5:21 PM ET

Thursday Night

Final
Tampa Bay 3-6Buccaneers24
at
Dallas 4-5Cowboys16
Spread DAL -9.5O/U 48.5ML TB +380 / DAL -500AT&T Stadium

International Game

Final
Philadelphia 2-7Eagles17
at
Jacksonville 6-2Jaguars19
Spread JAX -8.5O/U 41.5ML PHI +330 / JAX -425Tottenham Hotspur Stadium

Sunday Early

Final
Las Vegas 4-5Raiders17
at
New England 5-4Patriots45
Spread NE -3.5O/U 45.5ML LV +154 / NE -185Gillette Stadium
Final
Cincinnati 6-2Bengals31
at
Miami 1-7Dolphins24
Spread CIN -7O/U 43.5ML CIN -345 / MIA +275Hard Rock Stadium
Final
Indianapolis 2-7Colts22
at
Pittsburgh 6-2Steelers34
Spread PIT -3O/U 41.5ML IND +130 / PIT -155Acrisure Stadium
Final
New York 5-2-1Giants27
at
Washington 2-5-1Commanders27
Spread WAS -3.5O/U 41.5ML NYG +160 / WAS -192Northwest Stadium
Final
Minnesota 6-2Vikings23
at
New Orleans 3-5Saints13
Spread MIN -1.5O/U 41.5ML MIN -130 / NO +110Caesars Superdome
Final
Houston 3-5Texans26
at
Tennessee 1-7Titans3
Spread HOU -7O/U 37.5ML HOU -345 / TEN +275Nissan Stadium
Final
Cleveland 5-4Browns12
at
New York 2-7Jets17
Spread NYJ -2.5O/U 38.5ML CLE +114 / NYJ -135MetLife Stadium
Final
Chicago 7-2Bears7
at
Green Bay 6-3Packers31
Spread CHI -1.5O/U 47.5ML CHI -125 / GB +105Lambeau Field

Sunday Late

Final
Denver 7-2Broncos23
at
Los Angeles 0-8Chargers17
Spread DEN -3.5O/U 42.5ML DEN -180 / LAC +150SoFi Stadium
Final
San Francisco 7-149ers32
at
Seattle 5-4Seahawks29
Spread SEA -3O/U 46.5ML SF +140 / SEA -166Lumen Field
Final
Detroit 6-2Lions45
at
Arizona 3-6Cardinals21
Spread DET -5.5O/U 55.5ML DET -265 / ARI +215State Farm Stadium

Sunday Night

Final
Baltimore 4-5Ravens30
at
Atlanta 3-6Falcons23
Spread ATL -3O/U 43.5ML BAL +145 / ATL -175Mercedes-Benz Stadium

Monday Night

Final
Buffalo 7-1Bills37
at
Los Angeles 5-4Rams34
Spread LAR -3.5O/U 54.5ML BUF +145 / LAR -175SoFi Stadium

Run your own Week 5 pick'em

Start a free private pool with straight-up, confidence or against-the-spread scoring, or make your Week 5 picks in the free public pool. Need paper? Download the printable Week 5 pick'em sheet (free PDF).

Week 5 pick'em questions

What does the spread mean for pick'em?

The spread is how many points the favorite is expected to win by. In a straight-up pool it is only a guide; in an against-the-spread pool the favorite must win by more than the spread for the pick to count.

How do I run a Week 5 pick'em pool?

Start a free pool, pick straight-up, confidence or against-the-spread scoring, and share one invite link. Picks lock at kickoff and the standings update themselves as games end.

Is there a printable Week 5 pick'em sheet?

Yes. The Week 5 sheet has every game, kickoff times, a box per team and the tiebreaker, in winner, spread and confidence versions. It fills in the scores after the games.

Where do the lines come from?

Spreads, moneylines and totals come from a major US sportsbook feed, refreshed several times a week. They are for reference only; this site takes no bets.

Share