NFL Pick'em Week 2 2026: Games, Lines and Picks
NFL pick'em Week 2 of the 2026 season has 16 games, running from Thursday, September 17 to Monday, September 21 (times in Eastern). Every game is final, so this page is now the full Week 2 results sheet. Use the cards below to compare spreads, moneylines and totals before you lock in your picks.
Thursday Night
Sunday Early
Sunday Late
Sunday Night
Monday Night
Week schedule at a glance
| Kickoff (ET) | Matchup | Spread | O/U | Result |
|---|---|---|---|---|
| Thu Sep 17, 8:15 PM | Detroit Lions at Buffalo Bills | DET 31 at BUF 41 | ||
| Sun Sep 20, 1:00 PM | Carolina Panthers at Atlanta Falcons | CAR 34 at ATL 3 | ||
| Sun Sep 20, 1:00 PM | Cleveland Browns at Tampa Bay Buccaneers | CLE 23 at TB 19 | ||
| Sun Sep 20, 1:00 PM | Cincinnati Bengals at Houston Texans | CIN 20 at HOU 6 | ||
| Sun Sep 20, 1:00 PM | Minnesota Vikings at Chicago Bears | MIN 9 at CHI 3 | ||
| Sun Sep 20, 1:00 PM | Green Bay Packers at New York Jets | GB 20 at NYJ 17 | ||
| Sun Sep 20, 1:00 PM | New Orleans Saints at Baltimore Ravens | NO 24 at BAL 17 | ||
| Sun Sep 20, 1:00 PM | Philadelphia Eagles at Tennessee Titans | PHI 24 at TEN 20 | ||
| Sun Sep 20, 1:00 PM | Pittsburgh Steelers at New England Patriots | PIT 3 at NE 20 | ||
| Sun Sep 20, 4:05 PM | Las Vegas Raiders at Los Angeles Chargers | LV 26 at LAC 14 | ||
| Sun Sep 20, 4:05 PM | Jacksonville Jaguars at Denver Broncos | JAX 13 at DEN 20 | ||
| Sun Sep 20, 4:25 PM | Seattle Seahawks at Arizona Cardinals | SEA 31 at ARI 7 | ||
| Sun Sep 20, 4:25 PM | Washington Commanders at Dallas Cowboys | WAS 20 at DAL 37 | ||
| Sun Sep 20, 4:25 PM | Miami Dolphins at San Francisco 49ers | MIA 13 at SF 35 | ||
| Sun Sep 20, 8:20 PM | Indianapolis Colts at Kansas City Chiefs | IND 30 at KC 33 | ||
| Mon Sep 21, 8:15 PM | New York Giants at Los Angeles Rams | NYG 6 at LAR 28 |
Week 2 byes and lock times
No byes this week. All 32 teams play, so the maximum score is 16.
Locks: in a per-game pool the first lock is DET at BUF, Thursday 8:15 PM ET, and the last pick closes at Monday 8:15 PM ET. Whole-week pools lock everything at the first kickoff. The tiebreaker game is New York Giants at Los Angeles Rams.
Full season: 2026 bye weeks by team.
Run your own Week 2 pick'em
Start a free private pool with straight-up, confidence or against-the-spread scoring, or make your Week 2 picks in the free public pool. Need paper? Download the printable Week 2 pick'em sheet (free PDF).
Week 2 pick'em questions
How many NFL games are in Week 2 of 2026?
There are 16 games scheduled in Week 2, from Thursday, September 17 through Monday, September 21. Teams on a bye do not appear on this page.
When do the Week 2 games kick off?
Week 2 breaks down as 1 in the Thursday Night window, 8 in the Sunday Early window, 5 in the Sunday Late window, 1 in the Sunday Night window, 1 in the Monday Night window. All times on this page are Eastern; use the local-time button to convert.
What does the spread mean for pick'em?
The spread is the number of points the favorite is expected to win by. In a straight-up pool it is only a guide. In an against-the-spread pool the favorite must win by more than the spread for that pick to count.
When do picks lock in Week 2?
Most pools lock each game at its own kickoff, so Thursday picks lock first and Monday picks last. Check your pool rules, because some commissioners lock the whole week before the first Sunday game.
Where do the lines on this page come from?
Spreads, moneylines and totals are pulled from a major US sportsbook and refreshed several times a week. They are shown for reference; NFL Pickem Hub does not take bets.