NFL Pick'em Week 4 2026: Games, Lines and Picks
NFL pick'em Week 4 of the 2026 season has 16 games, running from Thursday, October 1 to Monday, October 5 (times in Eastern). The biggest favorite of the week is Baltimore Ravens by 10.5 over the Titans. Use the cards below to compare spreads, moneylines and totals before you lock in your picks.
Thursday Night
International Game
Sunday Early
Sunday Late
Sunday Night
Monday Night
Week schedule at a glance
| Kickoff (ET) | Matchup | Spread | O/U | Result |
|---|---|---|---|---|
| Thu Oct 1, 8:15 PM | Pittsburgh Steelers at Cleveland Browns | PIT -3 | 38.5 | |
| Sun Oct 4, 9:30 AM | Indianapolis Colts at Washington Commanders | IND -4.5 | 46.5 | |
| Sun Oct 4, 1:00 PM | New England Patriots at Buffalo Bills | BUF -5.5 | 49.5 | |
| Sun Oct 4, 1:00 PM | Los Angeles Rams at Philadelphia Eagles | LAR -1.5 | 45.5 | |
| Sun Oct 4, 1:00 PM | Green Bay Packers at Tampa Bay Buccaneers | |||
| Sun Oct 4, 1:00 PM | Dallas Cowboys at Houston Texans | HOU -3 | 47.5 | |
| Sun Oct 4, 1:00 PM | Tennessee Titans at Baltimore Ravens | BAL -10.5 | 44.5 | |
| Sun Oct 4, 1:00 PM | Arizona Cardinals at New York Giants | NYG -2.5 | 43.5 | |
| Sun Oct 4, 1:00 PM | New York Jets at Chicago Bears | CHI -3 | 43.5 | |
| Sun Oct 4, 1:00 PM | Jacksonville Jaguars at Cincinnati Bengals | CIN -3 | 49.5 | |
| Sun Oct 4, 4:05 PM | Miami Dolphins at Minnesota Vikings | MIN -10.5 | 42.5 | |
| Sun Oct 4, 4:25 PM | Kansas City Chiefs at Las Vegas Raiders | KC -6 | 45.5 | |
| Sun Oct 4, 4:25 PM | Denver Broncos at San Francisco 49ers | SF -3 | 45.5 | |
| Sun Oct 4, 4:25 PM | Los Angeles Chargers at Seattle Seahawks | SEA -6.5 | 42.5 | |
| Sun Oct 4, 8:20 PM | Detroit Lions at Carolina Panthers | DET -3 | 49.5 | |
| Mon Oct 5, 8:15 PM | Atlanta Falcons at New Orleans Saints |
Week 4 byes and lock times
No byes this week. All 32 teams play, so the maximum score is 16.
Locks: in a per-game pool the first lock is PIT at CLE, Thursday 8:15 PM ET, and the last pick closes at Monday 8:15 PM ET. Whole-week pools lock everything at the first kickoff. The tiebreaker game is Atlanta Falcons at New Orleans Saints.
Full season: 2026 bye weeks by team.
Run your own Week 4 pick'em
Start a free private pool with straight-up, confidence or against-the-spread scoring, or make your Week 4 picks in the free public pool. Need paper? Download the printable Week 4 pick'em sheet (free PDF).
Week 4 pick'em questions
How many NFL games are in Week 4 of 2026?
There are 16 games scheduled in Week 4, from Thursday, October 1 through Monday, October 5. Teams on a bye do not appear on this page.
When do the Week 4 games kick off?
Week 4 breaks down as 1 in the Thursday Night window, 1 in the International Game window, 8 in the Sunday Early window, 4 in the Sunday Late window, 1 in the Sunday Night window, 1 in the Monday Night window. All times on this page are Eastern; use the local-time button to convert.
What does the spread mean for pick'em?
The spread is the number of points the favorite is expected to win by. In a straight-up pool it is only a guide. In an against-the-spread pool the favorite must win by more than the spread for that pick to count.
When do picks lock in Week 4?
Most pools lock each game at its own kickoff, so Thursday picks lock first and Monday picks last. Check your pool rules, because some commissioners lock the whole week before the first Sunday game.
Where do the lines on this page come from?
Spreads, moneylines and totals are pulled from a major US sportsbook and refreshed several times a week. They are shown for reference; NFL Pickem Hub does not take bets.