NFL Pick'em Week 16 2026: Games, Lines and Picks
NFL pick'em Week 16 of the 2026 season has 16 games, running from Thursday, December 24 to Tuesday, December 29 (times in Eastern). Use the cards below to compare spreads, moneylines and totals before you lock in your picks.
Thursday Night
Friday
Sunday Early
Sunday Late
Sunday Night
Monday Night
Tuesday
Week schedule at a glance
| Kickoff (ET) | Matchup | Spread | O/U | Result |
|---|---|---|---|---|
| Thu Dec 24, 8:15 PM | Houston Texans at Philadelphia Eagles | |||
| Fri Dec 25, 1:00 PM | Green Bay Packers at Chicago Bears | |||
| Fri Dec 25, 4:30 PM | Buffalo Bills at Denver Broncos | |||
| Fri Dec 25, 8:15 PM | Los Angeles Rams at Seattle Seahawks | |||
| Sun Dec 27, 1:00 PM | New England Patriots at New York Jets | |||
| Sun Dec 27, 1:00 PM | Cleveland Browns at Baltimore Ravens | |||
| Sun Dec 27, 1:00 PM | Los Angeles Chargers at Miami Dolphins | |||
| Sun Dec 27, 1:00 PM | Arizona Cardinals at New Orleans Saints | |||
| Sun Dec 27, 4:05 PM | Tennessee Titans at Las Vegas Raiders | |||
| Sun Dec 27, 4:25 PM | San Francisco 49ers at Kansas City Chiefs | |||
| Sun Dec 27, 8:20 PM | Jacksonville Jaguars at Dallas Cowboys | |||
| Mon Dec 28, 8:15 PM | New York Giants at Detroit Lions | |||
| Tue Dec 29, 1:00 PM | Carolina Panthers at Pittsburgh Steelers | |||
| Tue Dec 29, 1:00 PM | Washington Commanders at Minnesota Vikings | |||
| Tue Dec 29, 1:00 PM | Tampa Bay Buccaneers at Atlanta Falcons | |||
| Tue Dec 29, 1:00 PM | Cincinnati Bengals at Indianapolis Colts |
Week 16 byes and lock times
No byes this week. All 32 teams play, so the maximum score is 16.
Locks: in a per-game pool the first lock is HOU at PHI, Thursday 8:15 PM ET, and the last pick closes at Tuesday 1:00 PM ET. Whole-week pools lock everything at the first kickoff. The tiebreaker game is Cincinnati Bengals at Indianapolis Colts.
Full season: 2026 bye weeks by team.
Run your own Week 16 pick'em
Start a free private pool with straight-up, confidence or against-the-spread scoring, or make your Week 16 picks in the free public pool. Need paper? Download the printable Week 16 pick'em sheet (free PDF).
Week 16 pick'em questions
How many NFL games are in Week 16 of 2026?
There are 16 games scheduled in Week 16, from Thursday, December 24 through Tuesday, December 29. Teams on a bye do not appear on this page.
When do the Week 16 games kick off?
Week 16 breaks down as 1 in the Thursday Night window, 3 in the Friday window, 4 in the Sunday Early window, 2 in the Sunday Late window, 1 in the Sunday Night window, 1 in the Monday Night window, 4 in the Tuesday window. All times on this page are Eastern; use the local-time button to convert.
What does the spread mean for pick'em?
The spread is the number of points the favorite is expected to win by. In a straight-up pool it is only a guide. In an against-the-spread pool the favorite must win by more than the spread for that pick to count.
When do picks lock in Week 16?
Most pools lock each game at its own kickoff, so Thursday picks lock first and Monday picks last. Check your pool rules, because some commissioners lock the whole week before the first Sunday game.
Where do the lines on this page come from?
Spreads, moneylines and totals are pulled from a major US sportsbook and refreshed several times a week. They are shown for reference; NFL Pickem Hub does not take bets.